Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284502 | 0.82 | TTR (0.41) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL1531949 | 0.79 | TTR (0.47) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL29436001 | 0.78 | TTR (0.59) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL7186092 | 0.77 | TTR (0.75) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL29492106 | 0.76 | TTR (0.57) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL6782741 | 0.75 | TTR (0.47) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL8125202 | 0.75 | ALDH1A1 (0.41) | TTRSLC6A2SLC6A3HPGDHSP90AA1 | |
| SCHEMBL9652575 | 0.72 | MAOA (0.45) | HPGDLMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8913702 | 0.72 | TTR (0.72) | TTRSLC6A2SLC6A3HPGDNR1I2 | |
| SCHEMBL29370878 | 0.72 | TTR (0.52) | TTRSLC6A2SLC6A3HPGDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015466-A | Dentifrices, mouthwashes | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-14 | — | — | US | claimed |
| US-4702916-A | AQUEOUS MIXTURE OF ALKLAI METAL SALT OF SATURATED FATTY ACID AND ALCOHOL AS VEHICLE | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| EP-0225848-A2 | Analgesic stick composition | WARNER-LAMBERT COMPANY (US) | 1987-06-16 | — | — | EP | claimed |
| EP-0099177-B1 | HALOGENOPHENYL GLYCERIDE ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-27 | — | — | EP | claimed |
| US-20120183619-A1 | TRICLOSAN DERIVATIVES AND NANOPARTICLES COMPRISING SAME | BAR ILAN UNIVERSITY (IL) | 2012-07-19 | — | — | US | disclosed |