Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220740 | 0.80 | IDO1 (0.38) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL16388285 | 0.80 | PIK3CA (0.45) | IDO1PNMTTAAR1CYP1A2CYP2D6 | |
| SCHEMBL9073026 | 0.78 | CYP3A4 (0.46) | IDO1PNMTSIGMAR1SMN1; SMN2 | |
| SCHEMBL2662792 | 0.78 | S1PR1 (0.41) | IDO1PNMTTAAR1SMN1; SMN2 | |
| SCHEMBL4226078 | 0.78 | IDO1 (0.37) | IDO1PNMTTAAR1SIGMAR1 | |
| SCHEMBL3298586 | 0.78 | IDO1 (0.64) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL17372921 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL407334 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL29494831 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL13179975 | 0.75 | L3MBTL1 (0.39) | IDO1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |
| US-5026895-A | For cultivated plants | BUDAPESTI VEGYIMUVEK (HU) | 1991-06-25 | — | — | US | disclosed |
| EP-0029123-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ANILINES, AND SUBSTITUTED ANILINES | BASF Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0029123-A1 | Process for the preparation of substituted anilines, and substituted anilines | BASF Aktiengesellschaft (DE) | 1981-05-27 | — | — | EP | disclosed |