Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820932 | 0.78 | APP (0.52) | PTPN1 | |
| SCHEMBL2908279 | 0.77 | HMGCR (0.50) | CYP3A4HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL14283818 | 0.77 | HMGCR (0.53) | CYP3A4HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL3957202 | 0.76 | HTT (0.69) | PTPN1CYP3A4HTTMEN1KMT2A | |
| SCHEMBL11155846 | 0.76 | PTPN1 (0.48) | PTPN1CYP3A4HTTMEN1KMT2A | |
| SCHEMBL14283785 | 0.75 | PDE4A (0.52) | CYP3A4HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL24805120 | 0.74 | POLB (0.51) | PTPN1CYP3A4HTTMEN1KMT2A | |
| SCHEMBL10908228 | 0.74 | ALDH1A1 (0.68) | PTPN1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL18377199 | 0.74 | SMPD1 (0.50) | PTPN1CYP3A4HTTMEN1KMT2A | |
| SCHEMBL23027375 | 0.74 | CYP19A1 (0.47) | PTPN1MEN1KMT2AHPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-5043354-A | Treatment of diseases caused by reactive oxygen species and organic radicals; antiischemic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0398142-A1 | New Benzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |