Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | OSBP | P22059 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714250 | 0.86 | PTPN1 (0.61) | APPPTPN1BACE1PPARGPPARA | |
| SCHEMBL9714237 | 0.86 | PTPN1 (0.61) | APPPTPN1BACE1PPARGPPARA | |
| SCHEMBL24804426 | 0.80 | PPARG (0.60) | APPPTPN1BACE1BCHEACHE | |
| SCHEMBL31312514 | 0.80 | BACE1 (0.55) | APPBACE1BCHEACHEPPARG | |
| SCHEMBL28442457 | 0.79 | OPRD1 (0.56) | APPPTPN1BACE1BCHEACHE | |
| SCHEMBL11650633 | 0.79 | APP (0.62) | APPPTPN1BACE1PPARGPPARA | |
| SCHEMBL5820976 | 0.79 | OPRD1 (0.56) | APPPTPN1BACE1BCHEACHE | |
| SCHEMBL7135772 | 0.79 | BACE1 (0.57) | APPPTPN1BACE1BCHEACHE | |
| SCHEMBL9788485 | 0.78 | PTPN1 (0.52) | PTPN1 | |
| Cymopol SCHEMBL21055681 | 0.78 | BACE1 (0.52) | APPPTPN1BACE1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034392-A2 | THERAPEUTIC QUINONES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-03-30 | — | — | WO | disclosed |