Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788612 | 1.00 | ESR1 (0.39) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL2931007 | 0.82 | CYP1A2 (0.32) | LMNAALOX5 | |
| SCHEMBL639800 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MMP3BCL2L1 | |
| SCHEMBL639799 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MMP3BCL2L1 | |
| SCHEMBL639798 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MMP3BCL2L1 | |
| SCHEMBL16807414 | 0.67 | ADAMTS4 (0.37) | ALDH1A1HPGDHSD17B10CA1CA2 | |
| SCHEMBL172436 | 0.66 | — | — | |
| SCHEMBL6744628 | 0.63 | KDM4E (0.43) | MAPTALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL2632693 | 0.61 | — | — | |
| SCHEMBL6260802 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985589-A | (1S-cis)-3-(4-hydroxyphenyl),5-cyclohexadiene-1,2-diol and corresponding acetate | GENERAL ELECTRIC COMPANY (US) | 1991-01-15 | — | — | US | claimed |
| US-4985589-A | (1S-cis)-3-(4-hydroxyphenyl),5-cyclohexadiene-1,2-diol and corresponding acetate | GENERAL ELECTRIC COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4985589-A | (1S-cis)-3-(4-hydroxyphenyl),5-cyclohexadiene-1,2-diol and corresponding acetate | GENERAL ELECTRIC COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4981793-A | Biological and chemical method for hydroxylating 4-substituted biphenyls and products obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4981793-A | Biological and chemical method for hydroxylating 4-substituted biphenyls and products obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1991-01-01 | — | — | US | disclosed |