Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50809 | 0.85 | CYP3A4 (0.62) | CYP3A4KDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL1866980 | 0.85 | KDM4E (0.67) | CYP3A4KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL29440769 | 0.85 | KDM4E (0.67) | CYP3A4KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL21921357 | 0.81 | CYP3A4 (0.58) | CYP3A4KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL8765708 | 0.81 | KDM4E (0.62) | CYP3A4KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL12094224 | 0.81 | TSHR (0.60) | CYP3A4KDM4ERAB9ATSHRALDH1A1 | |
| SCHEMBL511275 | 0.79 | CYP3A4 (0.50) | CYP3A4KDM4ERAB9ATSHRALDH1A1 | |
| SCHEMBL14106865 | 0.77 | KDM4E (0.40) | CYP3A4KDM4EMAPTMAPK1RAB9A | |
| SCHEMBL7751068 | 0.77 | TYR (0.50) | CYP3A4KDM4EMAPTTSHRKMT2A | |
| SCHEMBL2729632 | 0.76 | TSHR (0.64) | KDM4EMAPTMAPK1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021067-A | Rapid oxidation dyes for darkening hair; 5,6-dioxyindole derivatives | L'OREAL (FR) | 1991-06-04 | — | — | US | claimed |