Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.76 |
| ▸ | RAB9A | P51151 | 10/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | GFER | P55789 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 2/20 | 0.76 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.76 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | KDM5A | P29375 | 1/20 | 0.68 |
| ▸ | KDM5C | P41229 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788636 | 0.91 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31071669 | 0.88 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1691401 | 0.86 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5307300 | 0.86 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| Bromide SCHEMBL1691307 | 0.85 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12970131 | 0.82 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL396368 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL32682828 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12970091 | 0.80 | KDM4E (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13325772 | 0.80 | ALDH1A3 (0.87) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538087-B | Synthesis method of imidazopyridine compound | 温州大学新材料与产业技术研究院 | 2021-10-15 | — | — | CN | disclosed |
| US-4990506-A | Sedatives, anxiolytic, antiulcer, antistress | SYNTHELABO (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4891371-A | HYPNOTIC, ANXIOLYTIC, ANTI-STRESS ULCER | SYNTHELABO (FR) | 1990-01-02 | — | — | US | disclosed |
| US-4767755-A | NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1988-08-30 | — | — | US | disclosed |