Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9654007 | 0.99 | MAPT (0.49) | ALDH1A1L3MBTL1MAPK1MAPTPPIA | |
| SCHEMBL7439749 | 0.82 | POLB (0.50) | ALDH1A1MAPTKMT2AMEN1BCHE | |
| SCHEMBL7435438 | 0.80 | BCHE (0.49) | MAPTPPIAKMT2AMEN1ATM | |
| SCHEMBL2254514 | 0.77 | MAPT (0.53) | MAPTPPIAKMT2AMEN1ATM | |
| SCHEMBL7695939 | 0.76 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL4634622 | 0.75 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL10722003 | 0.74 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8053510 | 0.74 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL4935091 | 0.74 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL1414262 | 0.73 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075452-A | PROCESS FOR THE PREPARATION OF 5-MEMBERED NITROGEN CONTAINING HETEROAROMATICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-12-24 | — | — | US | disclosed |