Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612420 | 0.87 | BCHE (0.50) | POLBCYP1A2BCHEACHEPPID | |
| SCHEMBL7435438 | 0.85 | BCHE (0.49) | POLBBCHEACHEKMT2AMEN1 | |
| SCHEMBL9396517 | 0.85 | BCHE (0.54) | POLBCYP1A2BCHEACHEKMT2A | |
| Hydrochloric Acid SCHEMBL9651566 | 0.84 | BCHE (0.47) | POLBBCHEACHEKMT2AMEN1 | |
| SCHEMBL9788719 | 0.82 | ALDH1A1 (0.50) | BCHEACHEKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9654007 | 0.81 | MAPT (0.49) | CYP1A2BCHEACHEKMT2AMEN1 | |
| SCHEMBL28621243 | 0.78 | BCHE (0.51) | POLBCYP1A2BCHEACHEKMT2A | |
| SCHEMBL7840846 | 0.78 | KMT2A (0.54) | CYP1A2KMT2AMEN1LMNATSHR | |
| SCHEMBL2254514 | 0.76 | MAPT (0.53) | POLBCYP1A2BCHEACHEKMT2A | |
| SCHEMBL14490950 | 0.76 | KMT2A (0.55) | POLBCYP1A2PPIDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |