Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695924 | 0.72 | NPC1 (0.42) | HPGDRAB9ANPC1ALDH1A1CYP1A2 | |
| SCHEMBL4556562 | 0.72 | HSP90AA1 (0.49) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14302835 | 0.69 | CYP1A2 (0.51) | RAB9ANPC1MEN1KMT2ATSHR | |
| SCHEMBL9036919 | 0.68 | CYP1A2 (0.39) | HPGDRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL2936406 | 0.68 | MTNR1A (0.76) | NPC1KDM4EMT-CO2 | |
| SCHEMBL9156343 | 0.67 | CYP1A2 (0.55) | HPGDRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL29935885 | 0.67 | CYP1A2 (0.55) | HPGDRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL2937877 | 0.67 | SMN1; SMN2 (0.70) | HPGDRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL11467577 | 0.66 | MTNR1A (0.68) | KDM4EMT-CO2 | |
| Hydrochloric Acid SCHEMBL11157053 | 0.66 | CYP1A2 (0.53) | HPGDRAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030738-A | Synthesis of antiulcer compounds | JANUS FARMACEUTICI S.R.L. (IT) | 1991-07-09 | — | — | US | disclosed |
| EP-0269650-A1 | SYNTHESIS OF ANTIULCER COMPOUNDS | RECORDATI FARMA SRL (IT) | 1988-06-08 | — | — | EP | disclosed |