Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564515 | 0.89 | MAPT (0.46) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14564513 | 0.88 | MAPT (0.47) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL12920787 | 0.87 | MAPT (0.46) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL27713456 | 0.87 | MAPT (0.47) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL977511 | 0.86 | RAB9A (0.55) | MAPTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL977943 | 0.86 | MAPT (0.46) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL23367944 | 0.85 | MEN1 (0.56) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14564516 | 0.85 | MAPT (0.47) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL9225609 | 0.84 | MAPT (0.54) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL13210783 | 0.83 | NTRK1 (0.51) | MAPTKDM4EHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| US-20090099019-A1 | Thiazolecarboxanilides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-16 | — | — | US | claimed |
| US-20110004021-A1 | THIAZOLECARBOXANILIDES | DIETZ JOCHEN | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004021-A1 | THIAZOLECARBOXANILIDES | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MAPT 3011/4885KDM4E 2187/4885HTT 2031/4885 |
| US-20090099019-A1 | Thiazolecarboxanilides | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MAPT 3011/4885KDM4E 2187/4885HTT 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.