Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978883 | 0.86 | MAPT (0.47) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27713400 | 0.86 | RAB9A (0.55) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL975700 | 0.85 | KMT2A (0.55) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10213374 | 0.81 | KMT2A (0.52) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2911294 | 0.81 | CHRM3 (0.45) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210660 | 0.79 | F10 (0.53) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210780 | 0.79 | KMT2A (0.55) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210663 | 0.79 | RAB9A (0.59) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12263907 | 0.78 | RAB9A (0.58) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10213378 | 0.77 | L3MBTL1 (0.57) | RAB9ARECQLKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| US-20090099019-A1 | Thiazolecarboxanilides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-16 | — | — | US | claimed |
| US-20110004021-A1 | THIAZOLECARBOXANILIDES | DIETZ JOCHEN | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004021-A1 | THIAZOLECARBOXANILIDES | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | RAB9A 4174/4885RECQL 2730/4885KMT2A 1147/4885 |
| US-20090099019-A1 | Thiazolecarboxanilides | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | RAB9A 4174/4885RECQL 2730/4885KMT2A 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.