Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116420 | 0.85 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL25274064 | 0.85 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9684737 | 0.85 | LMNA (0.47) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10512529 | 0.85 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10377621 | 0.84 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL5080335 | 0.84 | KMT2A (0.46) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9457439 | 0.83 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9437372 | 0.83 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin9 SCHEMBL9186361 | 0.83 | DPP4 (0.66) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin9 SCHEMBL9186378 | 0.83 | DPP4 (0.66) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3066688-A | — | — | None | — | — | JP | disclosed |
| JP-H0366688-A | 1,4-DIHYDRO-4-OXONAPHTHYRIDINE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1991-03-22 | — | — | JP | disclosed |