Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.50 |
| ▸ | ATP4B | P51164 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788978 | 0.81 | ATP4A (0.53) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9789059 | 0.81 | ATP4A (0.53) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL8974692 | 0.80 | KMT2A (0.49) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9789061 | 0.79 | KMT2A (0.54) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9789066 | 0.78 | ATP4A (0.53) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9789012 | 0.77 | ATP4A (0.54) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9792753 | 0.75 | KMT2A (0.57) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9789098 | 0.73 | ATP4A (0.57) | ATP4AATP4BKMT2AGSTO1MAPT | |
| SCHEMBL7389239 | 0.72 | KMT2A (0.56) | ATP4AATP4BKMT2AMEN1L3MBTL1 | |
| SCHEMBL9789097 | 0.71 | ATP4A (0.59) | ATP4AATP4BKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259085-B1 | 2-GUANIDINO-4-ARYLTHIAZOLES FOR TREATMENT OF PEPTIC ULCERS | PFIZER INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5026715-A | 2-guanidino-4-arylthiazoles for treatment of peptic ulcers | PFIZER INC. (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0259085-A1 | 2-Guanidino-4-arylthiazoles for treatment of peptic ulcers | PFIZER INC. (US) | 1988-03-09 | — | — | EP | disclosed |