Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 2/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419838 | 0.91 | KMT2A (0.54) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL9792753 | 0.86 | KMT2A (0.57) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL9789061 | 0.76 | KMT2A (0.54) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL7423607 | 0.73 | GSTO1 (0.39) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL9788995 | 0.72 | ATP4A (0.50) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL3608090 | 0.72 | ALDH1A1 (0.49) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL8974692 | 0.70 | KMT2A (0.49) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL2380471 | 0.70 | MEN1 (0.49) | KMT2AMEN1NPSR1MAPTL3MBTL1 | |
| SCHEMBL9788978 | 0.69 | ATP4A (0.53) | KMT2AMEN1NPSR1MAPTHTT | |
| SCHEMBL9789059 | 0.69 | ATP4A (0.53) | KMT2AMEN1NPSR1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015438-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-1015438-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999011637-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-03-11 | — | — | WO | disclosed |