Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765881 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL250686 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL11638764 | 0.77 | CYP3A4 (0.59) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL8041829 | 0.77 | CYP3A4 (0.73) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL2264277 | 0.77 | ABL1 (0.53) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL2361415 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL5108252 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL8788030 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL9789351 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL7752080 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983772-A | 2-Methoxy-6-trifluoromethylaniline and 2,6-difluoro-3-methylaniline, intermediates to triazolo/1,5-a/pyrmidine-2-sulfonamide herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4954163-A | PRE-AND POSTEMERGENCE HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| US-4886883-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| US-4818273-A | Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides | THE DOW CHEMICAL COMPANY (US) | 1989-04-04 | — | — | US | disclosed |