Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | TFEB | P19484 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9789403 | 1.00 | LMNA (0.66) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL11341981 | 0.85 | KDM4E (0.68) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL1536281 | 0.85 | PTGER1 (0.66) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL11327707 | 0.85 | KDM4E (0.68) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL1536282 | 0.85 | PTGER1 (0.66) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL20446704 | 0.84 | LMNA (0.62) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL28300287 | 0.84 | LMNA (0.62) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL6388238 | 0.83 | LMNA (0.60) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL19244301 | 0.83 | LMNA (0.60) | LMNAMAPTSMN1; SMN2ATMAR | |
| SCHEMBL3536947 | 0.83 | SMN1; SMN2 (0.60) | LMNAMAPTSMN1; SMN2ATMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108481-A1 | THIAMINE COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 上海日馨生物科技有限公司 | 2020-06-04 | — | — | WO | disclosed |
| US-5045434-A | Addition polymer crosslinkable by exposure to argon laser light | KANSAI PAINT CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |