Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322632 | 0.73 | — | — | |
| SCHEMBL5322635 | 0.73 | — | — | |
| SCHEMBL7583787 | 0.71 | — | — | |
| SCHEMBL15482702 | 0.71 | — | — | |
| SCHEMBL7586719 | 0.71 | — | — | |
| Bicarbonate SCHEMBL28231169 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL4826000 | 0.69 | GABRP (0.36) | TSHRTP53EGLN1EGLN3KDM4E | |
| Bicarbonate SCHEMBL20423868 | 0.67 | — | — | |
| SCHEMBL27541122 | 0.63 | ALDH1A1 (0.43) | TSHRTP53KDM4ELMNA | |
| SCHEMBL104463 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049585-A | Certain 3,3-bis-(difluoro methyl)2,2-dimethyl-cyclopropane carboxylates having insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |