Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581927 | 1.00 | TRPV1 (0.44) | TRPV1SIRT2SIRT1CYP3A4CNR1 | |
| SCHEMBL27898826 | 0.78 | TRPV1 (0.50) | TRPV1CYP3A4 | |
| SCHEMBL23423341 | 0.76 | KMT2A (0.44) | TRPV1SIRT2SIRT1CYP3A4 | |
| SCHEMBL6558641 | 0.75 | TRPV1 (0.39) | TRPV1SIRT2SIRT1CYP3A4 | |
| SCHEMBL6559916 | 0.74 | TRPV1 (0.42) | TRPV1SIRT2SIRT1CYP3A4 | |
| SCHEMBL23363387 | 0.74 | TRPV1 (0.46) | TRPV1SIRT2SIRT1CYP3A4 | |
| SCHEMBL4257277 | 0.73 | CNR1 (0.54) | TRPV1SIRT2SIRT1CYP3A4CNR1 | |
| SCHEMBL13090968 | 0.71 | KMT2A (0.46) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL27898825 | 0.70 | HSD17B2 (0.53) | TRPV1CYP3A4 | |
| SCHEMBL7910107 | 0.70 | SIRT2 (0.43) | TRPV1SIRT2SIRT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |