Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910119 | 0.82 | CTSD (0.38) | SIRT2MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL7910113 | 0.75 | ALDH1A1 (0.37) | MAPTALDH1A1HTTTAAR1LMNA | |
| SCHEMBL7900352 | 0.74 | CTSD (0.38) | SIRT2MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL7908101 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1HTTTAAR1LMNA | |
| SCHEMBL7464900 | 0.73 | KCNE1 (0.52) | SIRT2ALDH1A1CTSDBACE1TRPV1 | |
| SCHEMBL7900347 | 0.73 | ALDH1A1 (0.39) | SIRT2MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL7910522 | 0.71 | KCNE1 (0.43) | SIRT2MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL6600843 | 0.71 | KCNE1 (0.43) | MAPTALDH1A1HTTTAAR1LMNA | |
| SCHEMBL7910189 | 0.70 | KCNE1 (0.41) | MAPTALDH1A1HTTTAAR1LMNA | |
| SCHEMBL7910178 | 0.70 | KCNE1 (0.42) | SIRT2MAPTALDH1A1HTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |