Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672293 | 0.75 | HPGD (0.50) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL9618117 | 0.72 | HPGD (0.54) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL11639714 | 0.68 | HPGD (0.55) | ALDH1A1HSD17B10RAB9ANPC1KDM4E | |
| SCHEMBL28124979 | 0.67 | HPGD (0.58) | ALDH1A1HSD17B10MAPTRAB9ANPC1 | |
| SCHEMBL1619109 | 0.66 | MAOB (0.67) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL30594160 | 0.66 | MAOB (0.67) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL11262049 | 0.65 | MAOB (0.57) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL8786718 | 0.65 | HPGD (0.55) | ALDH1A1HSD17B10MAPTRAB9ANPC1 | |
| SCHEMBL11394263 | 0.65 | SMN1; SMN2 (0.59) | ALDH1A1HSD17B10MAPTRAB9ANPC1 | |
| SCHEMBL11714053 | 0.64 | RAB9A (0.53) | ALDH1A1HSD17B10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3291280-A | — | — | None | — | — | JP | disclosed |
| JP-H03291280-A | THIOCHROMONE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1991-12-20 | — | — | JP | disclosed |