Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400027 | 1.00 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL9790042 | 1.00 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL595032 | 1.00 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL595031 | 1.00 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4762541 | 0.98 | GAA (0.50) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL403641 | 0.88 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL9721727 | 0.88 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL405104 | 0.88 | GAA (0.51) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL20599062 | 0.87 | SMN1; SMN2 (0.47) | GAANOS3NOS2CHRM1L3MBTL1 | |
| SCHEMBL30863789 | 0.85 | CHRNB2 (0.40) | GAATSHRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990521-A | Treating diarhea | JANSSEN PHARMACEUTICA (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0251417-A2 | 4-(aroylamino) piperidinebutanamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-01-07 | — | — | EP | disclosed |