SCHEMBL979035

SCHEMBL979035

Cc1c(C)c2c(c(C)c1OCc1ccccc1)C(CO)C(C)(C)O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNE1 P15382 3/20 0.38
KCNQ1 P51787 3/20 0.38
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
PTPN1 P18031 1/20 0.36
IDO1 P14902 1/20 0.34
POLB P06746 1/20 0.33
MAOB P27338 1/20 0.33
HPGD P15428 1/20 0.33
HPSE Q9Y251 1/20 0.32
HTR1A P08908 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
TSHR P16473 2/20 0.32
EDNRA P25101 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8867575 1.00 KCNE1 (0.38) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL8868743 1.00 KCNE1 (0.38) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL8867944 0.85 KCNE1 (0.38) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL8868048 0.85 IDO1 (0.38) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL6980167 0.85 KCNE1 (0.34) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL6968798 0.82 SPHK1 (0.45)
SCHEMBL6968802 0.82 SPHK1 (0.45)
SCHEMBL6975912 0.82 KCNE1 (0.37) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL6976195 0.82 KCNE1 (0.37) KCNE1KCNQ1MAPTMAPK1TDP1
SCHEMBL8867319 0.82 PTPN1 (0.40) KCNE1KCNQ1MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157088-B1 STABILIZED BLEACH COMPOSITIONS PROCTER & GAMBLE (US) 2006-01-11 EP claimed
US-6653270-B2 For bleaching/cleaning fabric PROCTER & GAMBLE COMPANY 2003-11-25 US claimed
CN-1177962-A Process for preparing 2, 3-dihydro-benzofuranol derivatives HOECHST MARION ROUSSEL INC (US) 1998-04-01 CN claimed
EP-0813530-A1 NOVEL PROCESS FOR PREPARING 2,3-DIHYDRO-BENZOFURANOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1997-12-29 EP claimed
US-5698696-A Process for preparing 2,3-dihydro-benzofuranol derivatives HOECHST MARION ROUSSEL, INC. (US) 1997-12-16 US claimed
WO-1996028437-A1 NOVEL PROCESS FOR PREPARING 2,3-DIHYDRO-BENZOFURANOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1996-09-19 WO claimed
EP-2292725-B2 Method of laundering fabrics at low temperature PROCTER & GAMBLE (US) 2022-08-24 EP disclosed
EP-2292725-B9 Method of laundering fabrics at low temperature PROCTER & GAMBLE (US) 2018-01-10 EP disclosed
EP-2292725-B1 Method of laundering fabrics at low temperature PROCTER & GAMBLE (US) 2016-04-13 EP disclosed
US-8586521-B2 Method of laundering fabrics at low temperature THE PROCTER & GAMBLE COMPANY (US) 2013-11-19 US disclosed
US-20120151684-A1 METHOD OF LAUNDERING FABRICS AT LOW TEMPERATURE PROCTER & GAMBLE COMPANY, THE 2012-06-21 US disclosed
EP-2451926-A1 COMPOSITIONS CONTAINING BLEACH CO-PARTICLES The Procter & Gamble Company (US) 2012-05-16 EP disclosed
EP-2451927-A1 PROCESS FOR MAKING BLEACH CO-PARTICLES The Procter & Gamble Company (US) 2012-05-16 EP disclosed
US-20030054968-A1 Air bleaching catalysts with enhancer and moderating agent UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-20 US disclosed
WO-2003010266-A1 POLYMER PRODUCTS UNILEVER N.V. (NL) 2003-02-06 WO disclosed
WO-2002072746-A1 BLEACHING CATALYSTS WITH UNSATURATED SURFACTANT AND ANTIOXIDANTS UNILEVER PLC (GB) 2002-09-19 WO disclosed
CN-1177962-A Process for preparing 2, 3-dihydro-benzofuranol derivatives HOECHST MARION ROUSSEL INC (US) 1998-04-01 CN disclosed
EP-0813530-A1 NOVEL PROCESS FOR PREPARING 2,3-DIHYDRO-BENZOFURANOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1997-12-29 EP disclosed
US-5698696-A Process for preparing 2,3-dihydro-benzofuranol derivatives HOECHST MARION ROUSSEL, INC. (US) 1997-12-16 US disclosed
WO-1996028437-A1 NOVEL PROCESS FOR PREPARING 2,3-DIHYDRO-BENZOFURANOL DERIVATIVES HOECHST MARION ROUSSEL, INC. (US) 1996-09-19 WO disclosed