Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL9790775 | 0.77 | FDPS (0.54) | — | |
| SCHEMBL9790770 | 0.77 | FDPS (0.60) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL9790811 | 0.75 | FDPS (0.61) | KDRCCNE1CDK2CDK5SCD | |
| Phosphonic Acid SCHEMBL9790585 | 0.74 | MAPT (0.49) | SCDGSTO1 | |
| SCHEMBL1745128 | 0.72 | LIMK1 (0.75) | KDRLIMK1 | |
| Phosphonic Acid SCHEMBL9790822 | 0.71 | ACP1 (0.56) | ACP1 | |
| SCHEMBL5703531 | 0.70 | CCNE1 (0.58) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL9790787 | 0.70 | KDR (0.53) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL10252594 | 0.69 | KDR (1.00) | KDRCCNE1CDK2CDK5SCD | |
| Phosphonic Acid SCHEMBL9790626 | 0.68 | FDPS (0.51) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |