Phosphonic Acid

Phosphonic Acid

SCHEMBL9790822

O=P(O)(O)CNc1nc2ccccc2s1.O=[PH](O)O.[NaH].[NaH]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.56
HPGD P15428 2/20 0.48
MAPK1 P28482 1/20 0.48
NPC1 O15118 7/20 0.48
RAB9A P51151 7/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 1/20 0.48
ADORA1 P30542 2/20 0.47
DYRK1A Q13627 1/20 0.47
MGLL Q99685 1/20 0.46
CASP3 P42574 2/20 0.46
SENP8 Q96LD8 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9790805 0.74 ACP1 (0.58) ACP1NPC1RAB9ASMN1; SMN2KMT2A
Phosphonic Acid SCHEMBL9790585 0.74 MAPT (0.49) MAPK1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL9790724 0.73 ACP1 (0.59) ACP1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL9367934 0.73 MGLL (0.57) ACP1HPGDMAPK1NPC1RAB9A
Phosphonic Acid SCHEMBL9790792 0.71 KDR (0.52) ACP1
SCHEMBL6640386 0.71 POLB (0.62) HPGDMAPK1NPC1RAB9ASMN1; SMN2
Phosphonic Acid SCHEMBL9790611 0.70 SCD (0.47) NPC1RAB9ASMN1; SMN2KMT2AMEN1
Phosphonic Acid SCHEMBL9790857 0.70 RAB9A (0.50) MAPK1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL1664350 0.70 NPC1 (0.67) HPGDMAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL11207220 0.70 NPC1 (0.67) HPGDMAPK1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057505-A Treatment of illnesses attributed to calcium metabolism disorders CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed