Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | AHCY | P23526 | 8/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580213 | 0.82 | ADORA1 (0.57) | ADORA1AHCYPRMT5WDR77ADORA3 | |
| SCHEMBL5580212 | 0.80 | ADORA1 (0.55) | ADORA1AHCYPRMT5WDR77ADORA3 | |
| SCHEMBL1071563 | 0.77 | ADORA1 (0.49) | ADORA1AHCYADORA3ADORA2B | |
| SCHEMBL29891224 | 0.76 | SLC28A1 (0.38) | — | |
| SCHEMBL7644145 | 0.75 | TAAR1 (0.44) | KMT2A | |
| SCHEMBL7813911 | 0.74 | ADORA1 (0.55) | ADORA1AHCYPRMT5WDR77ADORA2B | |
| SCHEMBL8601238 | 0.73 | ADORA1 (0.53) | ADORA1AHCYPRMT5WDR77ADORA3 | |
| SCHEMBL1068356 | 0.73 | ADORA1 (0.54) | ADORA1AHCYPRMT5WDR77ADORA3 | |
| SCHEMBL2111739 | 0.73 | TYMP (0.48) | ADORA1PRMT5WDR77ADORA2BADORA2A | |
| SCHEMBL9096320 | 0.72 | TYMP (0.56) | ADORA1PRMT5WDR77ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043430-A | Process for treating insoluble heterologous protein | TOSOH CORPORATION (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0329175-A1 | Human nerve growth factor gene segment | Tosoh Corporation (JP) | 1989-08-23 | — | — | EP | disclosed |