Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791008 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2ALOX5TBXA2RPTGER3 | |
| SCHEMBL9791075 | 0.86 | PTGER3 (0.48) | PTGS1PTGS2TBXA2RPTGER3PTGER2 | |
| SCHEMBL9791070 | 0.86 | PTGER3 (0.48) | PTGS1PTGS2TBXA2RPTGER3PTGER2 | |
| SCHEMBL9791294 | 0.81 | PTGER3 (0.56) | PTGS1PTGS2ALOX5TBXA2RPTGER3 | |
| SCHEMBL9791289 | 0.81 | PTGER3 (0.56) | PTGS1PTGS2ALOX5TBXA2RPTGER3 | |
| SCHEMBL9791029 | 0.80 | TBXA2R (0.56) | PTGS1PTGS2ALOX5TBXA2RPTGER3 | |
| SCHEMBL9791024 | 0.80 | TBXA2R (0.56) | PTGS1PTGS2ALOX5TBXA2RPTGER3 | |
| SCHEMBL9790998 | 0.74 | ALOX5 (0.41) | PTGS1PTGS2ALOX5 | |
| SCHEMBL9790993 | 0.74 | ALOX5 (0.41) | PTGS1PTGS2ALOX5 | |
| SCHEMBL9791072 | 0.71 | ALOX5 (0.41) | PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |