Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791029 | 1.00 | TBXA2R (0.56) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791023 | 0.85 | PTGER3 (0.73) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791019 | 0.85 | PTGER3 (0.73) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791289 | 0.82 | PTGER3 (0.56) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791294 | 0.82 | PTGER3 (0.56) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791008 | 0.80 | PTGS1 (0.39) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791010 | 0.80 | PTGS1 (0.39) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791047 | 0.80 | TBXA2R (0.38) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9791052 | 0.80 | TBXA2R (0.38) | TBXA2RPTGER3PTGER2PTGDRALOX5 | |
| SCHEMBL9790985 | 0.73 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |