Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.73 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGFR | P43088 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791023 | 1.00 | PTGER3 (0.73) | PTGER3PTGDRTBXA2RPTGER2SLC6A2 | |
| SCHEMBL9791294 | 0.87 | PTGER3 (0.56) | PTGER3PTGDRTBXA2RPTGER2PTGER4 | |
| SCHEMBL9791289 | 0.87 | PTGER3 (0.56) | PTGER3PTGDRTBXA2RPTGER2PTGER4 | |
| SCHEMBL9791024 | 0.85 | TBXA2R (0.56) | PTGER3PTGDRTBXA2RPTGER2SLC6A2 | |
| SCHEMBL9791029 | 0.85 | TBXA2R (0.56) | PTGER3PTGDRTBXA2RPTGER2SLC6A2 | |
| SCHEMBL7929816 | 0.84 | PTGER3 (1.00) | PTGER3PTGDRTBXA2RPTGER2SLC6A2 | |
| SCHEMBL7929810 | 0.84 | PTGER3 (1.00) | PTGER3PTGDRTBXA2RPTGER2SLC6A2 | |
| SCHEMBL9791070 | 0.81 | PTGER3 (0.48) | PTGER3PTGDRTBXA2RPTGER2PTGER4 | |
| SCHEMBL9791075 | 0.81 | PTGER3 (0.48) | PTGER3PTGDRTBXA2RPTGER2PTGER4 | |
| SCHEMBL3363365 | 0.74 | ALOX5 (0.73) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |