Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791078 | 1.00 | ALOX5 (0.40) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791071 | 0.91 | ALOX5 (0.40) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791067 | 0.91 | ALOX5 (0.40) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791073 | 0.87 | KAT8 (0.38) | — | |
| SCHEMBL9791231 | 0.81 | ALOX5 (0.44) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791236 | 0.81 | ALOX5 (0.44) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791020 | 0.81 | ALOX5 (0.41) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791072 | 0.81 | ALOX5 (0.41) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9790982 | 0.80 | ALOX5 (0.46) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9790978 | 0.80 | ALOX5 (0.46) | ALOX5LTB4RLTB4R2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |