Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790978 | 1.00 | ALOX5 (0.46) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9790985 | 0.91 | ALOX5 (0.46) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9790986 | 0.91 | ALOX5 (0.46) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791103 | 0.87 | PTGER3 (0.48) | ALOX5LTB4RLTB4R2BACE1 | |
| SCHEMBL9791098 | 0.87 | PTGER3 (0.48) | ALOX5LTB4RLTB4R2BACE1 | |
| SCHEMBL9790992 | 0.86 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9790994 | 0.86 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9791077 | 0.86 | LTB4R (0.39) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL9791081 | 0.86 | LTB4R (0.39) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL9791004 | 0.85 | PTGER3 (0.47) | ALOX5LTB4RLTB4R2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |