Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791012 | 0.81 | NPY2R (0.51) | ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9791006 | 0.81 | NPY2R (0.51) | ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9791043 | 0.80 | ALOX5 (0.48) | ALOX5PTGS2 | |
| SCHEMBL9791218 | 0.80 | ALOX5 (0.48) | ALOX5PTGS1PTGS2BACE1ITGB2 | |
| SCHEMBL9791169 | 0.80 | ALOX5 (0.48) | ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9791045 | 0.80 | ALOX5 (0.48) | ALOX5PTGS2 | |
| SCHEMBL3363362 | 0.80 | ALOX5 (0.73) | ALOX5PTGS1PTGS2BACE1ITGB2 | |
| SCHEMBL3363365 | 0.80 | ALOX5 (0.73) | ALOX5PTGS1PTGS2BACE1ITGB2 | |
| SCHEMBL9791017 | 0.78 | PTGS2 (0.48) | ALOX5PTGS2 | |
| SCHEMBL9791013 | 0.78 | PTGS2 (0.48) | ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |