Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791170 | 1.00 | PTGER3 (0.51) | PTGER3PTGER2PTGER4ALOX5ALDH1A1 | |
| SCHEMBL9791084 | 0.86 | PTGER4 (0.41) | PTGER3PTGER2PTGER4ALOX5PTGS1 | |
| SCHEMBL9791087 | 0.86 | PTGER4 (0.41) | PTGER3PTGER2PTGER4ALOX5PTGS1 | |
| SCHEMBL9791289 | 0.85 | PTGER3 (0.56) | PTGER3PTGER2PTGER4ALOX5PTGS1 | |
| SCHEMBL9791294 | 0.85 | PTGER3 (0.56) | PTGER3PTGER2PTGER4ALOX5PTGS1 | |
| SCHEMBL3251665 | 0.83 | PTGER3 (0.64) | PTGER3PTGER2PTGER4ALOX5ALDH1A1 | |
| SCHEMBL9791231 | 0.82 | ALOX5 (0.44) | ALOX5ALDH1A1PTGS1PTGS2NPC1 | |
| SCHEMBL9791236 | 0.82 | ALOX5 (0.44) | ALOX5ALDH1A1PTGS1PTGS2NPC1 | |
| SCHEMBL9790977 | 0.80 | ALOX5 (0.45) | ALOX5ALDH1A1PTGS1PTGS2 | |
| SCHEMBL9790982 | 0.78 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |