Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792209 | 0.91 | — | — | |
| SCHEMBL9792185 | 0.84 | BRD4 (0.47) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL9792190 | 0.78 | BRD4 (0.52) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL9792162 | 0.74 | — | — | |
| SCHEMBL2618364 | 0.74 | ALDH1A1 (0.50) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL2618383 | 0.71 | BRD4 (0.53) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL9792175 | 0.68 | GRIN1 (0.47) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL16512494 | 0.68 | BRD4 (0.64) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL9792170 | 0.68 | ALDH1A1 (0.39) | BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL2602375 | 0.68 | AKT1 (0.68) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066654-A | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-11-19 | — | — | US | claimed |