Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.36 |
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501603 | 0.82 | GRIN1 (0.46) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL9792617 | 0.79 | GAA (0.41) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| Iodomethane SCHEMBL9792638 | 0.77 | GAA (0.40) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL11696440 | 0.72 | GRIN1 (0.40) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL10816606 | 0.70 | GRIN1 (0.41) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL9698509 | 0.70 | ESR2 (0.42) | ADRA1AADRA1BGRIN1GRIN2A | |
| SCHEMBL10875203 | 0.68 | GRIN1 (0.36) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL750050 | 0.66 | ADRA1A (0.37) | ADRA1AADRA1BHTR1AADRA1DGAA | |
| SCHEMBL11697625 | 0.65 | TSHR (0.40) | ADRA1AADRA1BCYP3A4 | |
| SCHEMBL14039677 | 0.65 | GRIN1 (0.45) | ADRA1AADRA1BHTR1AADRA1DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062883-A | Fungicides, herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-11-05 | — | — | US | disclosed |
| US-5000778-A | 2-aryl-2-(3-pyridyl)-1,3-dioxalanes, dithiolanes and -oxa-thiolanes having herbicidal and pesticidal activity | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4940483-A | Fungicidal 2-(-3-pyridyl)-1,3-dioxanes | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0315839-A2 | 3-Substituted pyridines | NIHON BAYER AGROCHEM K.K. (JP) | 1989-05-17 | — | — | EP | disclosed |