SCHEMBL750050

SCHEMBL750050

CC1COC(c2ccccc2)(c2ccccc2CO)O1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 11/20 0.37
ADRA1B P35368 9/20 0.37
HTR1A P08908 8/20 0.37
ADRA1D P25100 8/20 0.37
CHRNB2 P17787 1/20 0.35
SLC6A2 P23975 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
SLC6A3 Q01959 1/20 0.35
GAA P10253 1/20 0.34
HSD17B10 Q99714 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
OPRL1 P41146 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL748993 0.86 CYP1A2 (0.39) ADRA1AADRA1BHTR1AADRA1DCHRNB2
SCHEMBL749991 0.85 ADRA1A (0.43) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL748670 0.83 HTR1A (0.43) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL749621 0.82 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL3412898 0.81 ADRA1A (0.43) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL10501603 0.80 GRIN1 (0.46) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL752340 0.80 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL4323822 0.79 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL750523 0.79 ADRA1A (0.41) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL749307 0.78 ADRA1A (0.41) ADRA1AADRA1BHTR1AADRA1DGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US claimed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed