SCHEMBL979281

SCHEMBL979281

O=C(C=Cc1ccco1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.76
KDM4E B2RXH2 5/20 0.76
ALDH1A1 P00352 5/20 0.76
KMT2A Q03164 5/20 0.76
POLB P06746 4/20 0.76
RAB9A P51151 3/20 0.76
MEN1 O00255 3/20 0.76
MAOB P27338 2/20 0.73
MAOA P21397 1/20 0.73
HCAR2 Q8TDS4 1/20 0.68
NPC1 O15118 3/20 0.68
HPGD P15428 2/20 0.68
LMNA P02545 2/20 0.68
NFKB1 P19838 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
PTPN1 P18031 1/20 0.68
PKM P14618 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8290646 1.00 MAPT (0.76) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11413572 1.00 MAPT (0.76) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11701729 0.93 MAPT (0.87) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11701738 0.93 MAPT (0.87) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11474332 0.91 MAPT (0.79) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11473225 0.91 MAPT (0.79) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL5597969 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL10507733 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL10944213 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL14458244 0.86 KMT2A (0.67) MAPTKDM4EALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101494999-A Method for using organic compound GIVAUDAN SA (CH) 2009-07-29 CN claimed
EP-1051910-A2 The treatment of pests using certain ethylenically-unsaturated carbonyl compounds Sorex Limited (GB) 2000-11-15 EP claimed
CN-111925324-B Synthetic method of 3-acyl quinoline compound 南通大学 2022-07-29 CN disclosed
EP-3749657-A1 A PROCESS FOR THE PREPARATION OF PYRYLIUM SALTS Council of Scientific & Industrial Research (IN) 2020-12-16 EP disclosed
CN-111925324-A Synthetic method of 3-acyl quinoline compound 南通大学 2020-11-13 CN disclosed
WO-2019155485-A1 A PROCESS FOR THE PREPARATION OF PYRYLIUM SALTS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-08-15 WO disclosed
US-10201879-B2 Silver paste composition and semiconductor device using same HITACHI CHEMICAL COMPANY, LTD. (JP) 2019-02-12 US disclosed
EP-2894641-B1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME HITACHI CHEMICAL CO LTD (JP) 2017-07-26 EP disclosed
US-9138427-B2 Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents NIVALIS THERAPEUTICS, INC. (US) 2015-09-22 US disclosed
US-20150217411-A1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME RESONAC CORPORATION (JP) 2015-08-06 US disclosed
EP-2894641-A1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME Hitachi Chemical Company, Ltd. (JP) 2015-07-15 EP disclosed
EP-1051910-A2 The treatment of pests using certain ethylenically-unsaturated carbonyl compounds Sorex Limited (GB) 2000-11-15 EP disclosed
EP-0662968-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-07-19 EP disclosed
EP-0662968-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS. PPG INDUSTRIES INC (US) 1995-04-12 EP disclosed
WO-1994007889-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1994-04-14 WO disclosed
US-5274132-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1993-12-28 US disclosed
US-5037824-A Cardiotonic, antiischemic agents FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-08-06 US disclosed
EP-0320628-A1 Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase ABBOTT LABORATORIES (US) 1989-06-21 EP disclosed
US-4193905-A Curable epoxide resin mixtures containing diaminopropanes CIBA-GEIGY CORPORATION (US) 1980-03-18 US disclosed
US-4016114-A Heat-stable cellular materials RHONE-POULENC INDUSTRIES (FR) 1977-04-05 US disclosed