SCHEMBL8290646

SCHEMBL8290646

O=C(/C=C/c1ccco1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.76
KDM4E B2RXH2 5/20 0.76
ALDH1A1 P00352 5/20 0.76
KMT2A Q03164 5/20 0.76
POLB P06746 4/20 0.76
RAB9A P51151 3/20 0.76
MEN1 O00255 3/20 0.76
MAOB P27338 2/20 0.73
MAOA P21397 1/20 0.73
HCAR2 Q8TDS4 1/20 0.68
NPC1 O15118 3/20 0.68
HPGD P15428 2/20 0.68
LMNA P02545 2/20 0.68
NFKB1 P19838 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
PTPN1 P18031 1/20 0.68
PKM P14618 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979281 1.00 MAPT (0.76) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11413572 1.00 MAPT (0.76) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11701729 0.93 MAPT (0.87) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11701738 0.93 MAPT (0.87) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11474332 0.91 MAPT (0.79) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL11473225 0.91 MAPT (0.79) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL5597969 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL10507733 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL10944213 0.86 MAPT (1.00) MAPTKDM4EALDH1A1KMT2APOLB
SCHEMBL14458244 0.86 KMT2A (0.67) MAPTKDM4EALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192224-A Alpha, beta-unsaturated ketone cyano silanization method and application 哈尔滨理工大学 2024-12-27 CN claimed
CN-119192224-A Alpha, beta-unsaturated ketone cyano silanization method and application 哈尔滨理工大学 2024-12-27 CN disclosed
EP-2810198-B1 ANTI-INVASIVE COMPOUNDS UNIV GENT (BE) 2023-07-12 EP disclosed
US-11661407-B2 Process for the preparation of pyrylium salts COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2023-05-30 US disclosed
CN-108623425-B Method for constructing four-membered ring by visible light catalysis [2+2] reaction 中国科学院理化技术研究所 2021-05-14 CN disclosed
US-20210087158-A1 A PROCESS FOR THE PREPARATION OF PYRYLIUM SALTS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2021-03-25 US disclosed
US-10201879-B2 Silver paste composition and semiconductor device using same HITACHI CHEMICAL COMPANY, LTD. (JP) 2019-02-12 US disclosed
EP-2894641-B1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME HITACHI CHEMICAL CO LTD (JP) 2017-07-26 EP disclosed
US-20150217411-A1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME RESONAC CORPORATION (JP) 2015-08-06 US disclosed
EP-2894641-A1 SILVER PASTE COMPOSITION AND SEMICONDUCTOR DEVICE USING SAME Hitachi Chemical Company, Ltd. (JP) 2015-07-15 EP disclosed
US-20070037752-A1 Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases KEYNEUROTEK PHARMACEUTICALS AG (DE) 2007-02-15 US disclosed
US-20070037752-A1 Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases KEYNEUROTEK PHARMACEUTICALS AG (DE) 2007-02-15 US disclosed
WO-2005037779-A2 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES IMTM GMBH (DE) 2005-04-28 WO disclosed
WO-2005037257-A2 NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES IMTM GMBH (DE) 2005-04-28 WO disclosed
WO-2005034940-A2 DUAL ALANYL AMINOPEPTIDASE AND DIPEPTIDYL PEPTIDASE IV INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND FOR TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL AND OTHER DISEASES IMTM GMBH (DE) 2005-04-21 WO disclosed
EP-0662968-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-07-19 EP disclosed
EP-0662968-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS. PPG INDUSTRIES INC (US) 1995-04-12 EP disclosed
WO-1994007889-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1994-04-14 WO disclosed
US-5274132-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1993-12-28 US disclosed
US-5037824-A Cardiotonic, antiischemic agents FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210087158-A1 A PROCESS FOR THE PREPARATION OF PYRYLIUM SALTS IPO5, SF3B5, CYP4F11 MAPT 2365/4885KDM4E 1880/4885ALDH1A1 2811/4885
US-20070037752-A1 Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases DNPEP, PREP, ANPEP MAPT 1400/4885KDM4E 3461/4885ALDH1A1 1025/4885
US-11661407-B2 Process for the preparation of pyrylium salts SF3B5, IPO5, CYP4F11 MAPT 2455/4885KDM4E 1721/4885ALDH1A1 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.