Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 0.74 |
| ▸ | MAOB | P27338 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944213 | 1.00 | MAPT (1.00) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL10507733 | 1.00 | MAPT (1.00) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11701729 | 0.93 | MAPT (0.87) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11701738 | 0.93 | MAPT (0.87) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11473225 | 0.88 | MAPT (0.79) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11474332 | 0.88 | MAPT (0.79) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL979281 | 0.86 | MAPT (0.76) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8290646 | 0.86 | MAPT (0.76) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11413572 | 0.86 | MAPT (0.76) | MAPTKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL15155402 | 0.85 | MAOA (1.00) | MAPTKMT2AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343024-A | Chalcone derivative containing benzoxazole structure and preparation method and application thereof | 贵州大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116730954-A | Isopropanolamine compound containing chalcone structure, and preparation method and application thereof | 贵州大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114085199-B | Chalcone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-114085199-A | Chalcone derivative containing sulfonyl piperazine and preparation method and application thereof | 贵州大学 | 2022-02-25 | — | — | CN | disclosed |
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-7119120-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-10-10 | — | — | US | disclosed |
| US-20040019113-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| EP-0142463-B1 | METHOD OF PRODUCING PREPREGS AND COMPOSITE MATERIALS REINFORCED THEREWITH | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |
| EP-0115471-B1 | IMAGE-FORMING PROCESS | CIBA-GEIGY AG (CH) | 1988-02-10 | — | — | EP | disclosed |
| EP-0126029-B1 | IMAGE-FORMING PROCESS | CIBA-GEIGY AG (CH) | 1987-08-26 | — | — | EP | disclosed |
| US-4572890-A | Process for the production of images | CIBA-GEIGY CORPORATION (US) | 1986-02-25 | — | — | US | disclosed |
| US-4552604-A | EPOXY RESINS, PHOTOPOLYMERIZATION, LAMINATION | CIBA GEIGY CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4546067-A | Image production utilizing multifunctional light sensitive compounds | CIBA GEIGY CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0142463-A2 | Method of producing prepregs and composite materials reinforced therewith | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | disclosed |
| US-4500629-A | Method of forming images from liquid masses | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0115471-A2 | Image-forming process | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |
| US-4252593-A | Method of preparing reinforced composites | CIBA-GEIGY CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-4181807-A | Polymerizable esters derived from a glycidyl ether of a phenolic unsaturated ketone | CIBA-GEIGY CORPORATION (US) | 1980-01-01 | — | — | US | disclosed |
| US-4179577-A | Polymerisable esters derived from a phenolic unsaturated ketone | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019113-A1 | Phosphate transport inhibitors | SLC34A1, SLC34A2, SLC20A1 | MAPT 3148/4885KMT2A 4536/4885KDM4E 4292/4885 |
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | MAPT 3058/4885KMT2A 4634/4885KDM4E 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.