Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794550 | 0.81 | SOAT1 (0.45) | RAB9AALDH1A1NPC1PPARGPPARA | |
| SCHEMBL27483570 | 0.81 | MEN1 (0.45) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27483569 | 0.79 | MEN1 (0.45) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9363884 | 0.77 | RIPK1 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29480057 | 0.74 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9337221 | 0.73 | RIPK1 (0.46) | ALDH1A1PPARGPPARA | |
| SCHEMBL9340629 | 0.73 | RIPK1 (0.46) | CYP3A4RAB9APOLB | |
| SCHEMBL9364207 | 0.73 | RIPK1 (0.39) | ALDH1A1MLYCD | |
| SCHEMBL9340727 | 0.72 | RIPK1 (0.44) | ALDH1A1PPARGPPARA | |
| SCHEMBL9794539 | 0.72 | RIPK1 (0.50) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075467-A | Reacting organotitanium halide with lithium amide | CIBA-GEIGY CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |