Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337221 | 0.86 | RIPK1 (0.46) | RIPK1ALDH1A1SOAT1 | |
| SCHEMBL9359593 | 0.84 | CYP3A4 (0.43) | RIPK1ALDH1A1SOAT1MLYCDHTR7 | |
| SCHEMBL9794550 | 0.84 | SOAT1 (0.45) | RIPK1ALDH1A1SOAT1 | |
| SCHEMBL9340727 | 0.82 | RIPK1 (0.44) | RIPK1ALDH1A1SOAT1 | |
| SCHEMBL9794539 | 0.82 | RIPK1 (0.50) | RIPK1SOAT1 | |
| SCHEMBL11256305 | 0.80 | THRA (0.38) | ALDH1A1MLYCD | |
| SCHEMBL11427360 | 0.76 | SOAT1 (0.39) | ALDH1A1SOAT1HTR7 | |
| SCHEMBL5537674 | 0.74 | CES2 (0.42) | RIPK1ALDH1A1 | |
| SCHEMBL9363884 | 0.74 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL9794587 | 0.73 | MEN1 (0.47) | ALDH1A1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318893-B1 | Titanocenes, their use and N-substituted fluoroanilines | CIBA GEIGY AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| US-5026625-A | Photoinitiators for polymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |