Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497692 | 0.94 | KMT2A (0.53) | KMT2AMEN1GNAI3GNAO1GNAI1 | |
| SCHEMBL15808518 | 0.81 | — | — | |
| SCHEMBL28224175 | 0.81 | — | — | |
| SCHEMBL823169 | 0.79 | CYP2D6 (0.50) | KMT2AGNAI3GNAO1GNAI1PAOX | |
| SCHEMBL9414030 | 0.79 | MEN1 (0.59) | KMT2AMEN1GNAI3GNAO1GNAI1 | |
| SCHEMBL766293 | 0.78 | PAOX (0.44) | KMT2AGNAI3GNAO1GNAI1PAOX | |
| SCHEMBL8354456 | 0.78 | DPP7 (0.50) | GNAI3GNAO1GNAI1PAOXDPP7 | |
| SCHEMBL3891776 | 0.77 | PAOX (0.45) | KMT2AMEN1GNAI3GNAO1GNAI1 | |
| SCHEMBL14169289 | 0.77 | ALDH1A1 (0.56) | KMT2AMEN1GNAI3GNAO1GNAI1 | |
| SCHEMBL8533026 | 0.76 | KMT2A (0.67) | KMT2AMEN1DPP7CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |