Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650885 | 0.93 | PAOX (0.57) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL22171084 | 0.92 | PAOX (0.47) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL22171086 | 0.92 | PAOX (0.47) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL15858573 | 0.91 | PAOX (0.61) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL14228092 | 0.91 | PAOX (0.61) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL17175237 | 0.91 | PAOX (0.61) | CYP2D6CYP2C9CYP2C19KMT2APAOX | |
| SCHEMBL22203843 | 0.90 | PAOX (0.50) | CYP2C9CYP2C19KMT2APAOXGNAI3 | |
| SCHEMBL3088754 | 0.86 | — | — | |
| SCHEMBL861034 | 0.85 | KMT2A (0.57) | CYP2D6CYP2C9CYP2C19KMT2ADPP7 | |
| SCHEMBL22917014 | 0.85 | KMT2A (0.57) | CYP2D6CYP2C9CYP2C19KMT2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2023073711-A1 | COLLAGEN-CONTAINING CURABLE FORMULATIONS | COLLPLANT LTD. (IL) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022087317-A1 | THIOHYDROXYPYRIDINE CHELATES | LUMIPHORE, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| EP-3129350-B1 | MACROCYCLES | LUMIPHORE INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-11130865-B2 | Rhodamine dyes and conjugates | PHARMACOPHOTONICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| US-7939664-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS INC. (US) | 2011-05-10 | — | — | US | disclosed |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-20070032653-A1 | N-{1-(4-(3-bromophenyl)-1H-imidazol-2-yl)-5-methylhexyl}-N-cyclohexylamine; agonists or antagonists of somatostatin receptors; acromegaly, restenosis, Crohn's disease, systemic sclerosis, external and internal pancreatic pseudocysts and ascites, nesidoblastosis, hyperinsulinism, gastrinoma, etc. | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2007-02-08 | — | — | US | disclosed |
| US-4387099-A | Alkanolamine derivatives | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |
| US-4327113-A | DRUGS FOR TREATMENT OF HEART DISEASES, ADRENERGIC BLOCKING AGENTS, ETC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-27 | — | — | US | disclosed |
| US-4260632-A | ADRENERGIC BLOCKING AGENTS, CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-07 | — | — | US | disclosed |
| US-4221807-A | ADRENERGIC BLOCKING AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-09-09 | — | — | US | disclosed |
| US-4141987-A | HYPOTENSIVE, ADRENERGIC BLOCKING AGENT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | disclosed |
| US-4131685-A | ADRENERGIC BLOCKING AGENT, CARDIAC STIMULANT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | CYP2D6 4673/4885CYP2C9 4755/4885CYP2C19 4692/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | CYP2D6 3692/4885CYP2C9 4446/4885CYP2C19 4508/4885 |
| US-11130865-B2 | Rhodamine dyes and conjugates | RCN1, RDX, CIT | CYP2D6 324/4885CYP2C9 656/4885CYP2C19 557/4885 |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | CYP2D6 4673/4885CYP2C9 4755/4885CYP2C19 4692/4885 |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | CYP2D6 976/4885CYP2C9 2993/4885CYP2C19 3935/4885 |
| US-20070032653-A1 | N-{1-(4-(3-bromophenyl)-1H-imidazol-2-yl)-5-methylhexyl}-N-cyclohexylamine; agonists or antagonists of somatostatin receptors; acromegaly, restenosis, Crohn's disease, systemic sclerosis, external and internal pancreatic pseudocysts and ascites, nesidoblastosis, hyperinsulinism, gastrinoma, etc. | GHSR, IGF1R, GIPR | CYP2D6 3845/4885CYP2C9 4546/4885CYP2C19 3989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.