Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795486 | 0.82 | — | — | |
| SCHEMBL9795220 | 0.79 | — | — | |
| SCHEMBL9499958 | 0.78 | KDM4E (0.38) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL9497845 | 0.78 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL27837325 | 0.75 | KDM4E (0.41) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL9795415 | 0.75 | KDM4E (0.35) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL9795141 | 0.75 | SMN1; SMN2 (0.31) | HSD17B10 | |
| Oxalic Acid SCHEMBL9795145 | 0.74 | KDM4E (0.38) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL9501573 | 0.74 | KDM4E (0.40) | KDM4ECYP2D6HSD17B10 | |
| SCHEMBL10309174 | 0.72 | SMN1; SMN2 (0.45) | KDM4ECYP2D6LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |