Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907142 | 0.87 | HSD17B10 (0.31) | SMN1; SMN2HSD17B10 | |
| SCHEMBL9795545 | 0.78 | SMYD3 (0.33) | SMN1; SMN2HSD17B10 | |
| SCHEMBL2746180 | 0.76 | SMN1; SMN2 (0.34) | SMN1; SMN2HSD17B10TSHR | |
| SCHEMBL9497924 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL9795151 | 0.75 | KDM4E (0.33) | HSD17B10 | |
| SCHEMBL9795486 | 0.74 | — | — | |
| SCHEMBL15081428 | 0.74 | — | — | |
| SCHEMBL26783485 | 0.73 | BCHE (0.36) | — | |
| SCHEMBL9795370 | 0.73 | IDO1 (0.33) | SMN1; SMN2 | |
| SCHEMBL9795332 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |