Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 9/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921029 | 0.77 | — | — | |
| SCHEMBL8957333 | 0.77 | GSR (0.50) | GSRCA2MAPTALDH1A1 | |
| SCHEMBL28654963 | 0.76 | ANPEP (0.43) | ANPEPENPEPSLC6A1GABRA5GABRB2 | |
| SCHEMBL13245814 | 0.76 | ANPEP (0.43) | ANPEPENPEPSLC6A1GABRA5GABRB2 | |
| SCHEMBL9795057 | 0.75 | EPHX2 (0.33) | GSR | |
| SCHEMBL23927596 | 0.75 | GSR (0.42) | GSRGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL2012678 | 0.75 | GSR (0.42) | GSRGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL11059646 | 0.75 | GSR (0.38) | GSRCA2MAPTALDH1A1 | |
| SCHEMBL9019578 | 0.75 | GSR (0.38) | GSRCA2MAPTALDH1A1 | |
| SCHEMBL24483431 | 0.74 | ANPEP (0.56) | ANPEPENPEPSLC6A1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |