Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770967 | 0.81 | MAPK1 (0.73) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL5655910 | 0.78 | MAPK1 (0.51) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL9795278 | 0.73 | CYP3A4 (0.41) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL16013709 | 0.73 | MIF (0.45) | TDP1MAPK1CYP3A4PTPRCDHODH | |
| SCHEMBL240228 | 0.72 | CYP3A4 (0.42) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL8853900 | 0.71 | MAPK1 (0.58) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL9795282 | 0.70 | CYP3A4 (0.38) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL11351193 | 0.70 | CYP2C19 (0.50) | TDP1MAPK1CYP3A4TRPA1PTPRC | |
| SCHEMBL58874 | 0.69 | MAPK1 (1.00) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL29376406 | 0.69 | MAPK1 (1.00) | TDP1MAPK1CYP3A4TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045226-A | Reaction product of tin compound with sulfonyl isocyanate, storage stability, polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |