Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795251 | 0.81 | CNR1 (0.39) | ALDH1A1CNR1MEN1KMT2AGAA | |
| SCHEMBL1515376 | 0.77 | HPGD (0.43) | ALDH1A1CNR1MEN1KMT2AGAA | |
| Oxalic Acid SCHEMBL9795360 | 0.76 | CNR1 (0.36) | ALDH1A1CNR1MEN1KMT2AUSP2 | |
| SCHEMBL1515653 | 0.74 | CNR1 (0.35) | ALDH1A1CNR1MEN1KMT2AGAA | |
| SCHEMBL5169773 | 0.74 | CNR1 (0.42) | ALDH1A1CNR1MEN1KMT2AGAA | |
| Oxalic Acid SCHEMBL9795456 | 0.74 | MEN1 (0.36) | ALDH1A1MEN1KMT2AHSD17B10ALOX15 | |
| SCHEMBL22236865 | 0.74 | CNR1 (0.37) | ALDH1A1CNR1MEN1KMT2AGAA | |
| SCHEMBL12478169 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CNR1MEN1KMT2AGAA | |
| SCHEMBL21243991 | 0.73 | DNM1 (0.47) | ALDH1A1USP2KDM4E | |
| SCHEMBL2237590 | 0.73 | OTC (0.44) | KMT2ABLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |