SCHEMBL9795342

SCHEMBL9795342

CC(C)(N)C(=O)NC1CCCCC1OC(=O)C(=O)OC1CCCCC1NC(=O)C(C)(C)N

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9795429 0.79 GSR (0.45)
SCHEMBL9500143 0.79 GSR (0.45)
SCHEMBL9497720 0.76 CNR1 (0.37) PDK1PDK2PDK3PDK4
SCHEMBL9795241 0.74 IDO1 (0.33)
Oxalic Acid SCHEMBL9795338 0.72 CNR1 (0.35) PDK1PDK2PDK3PDK4
Oxalic Acid SCHEMBL9795329 0.72 CNR1 (0.35) PDK1PDK2PDK3PDK4
SCHEMBL9795142 0.72 EPHX1 (0.31)
SCHEMBL9795409 0.70 EPHX1 (0.37) PDK1PDK2PDK3PDK4
SCHEMBL14243258 0.70 PDK1 (0.59) PDK1PDK2PDK3PDK4
SCHEMBL29315346 0.67 KMT2A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037849-A For treatment of heart and circulatory diseases BOEHRINGER MANNHEIM GMBH (DE) 1991-08-06 US disclosed