Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ADA | P00813 | 5/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795329 | 1.00 | CNR1 (0.35) | CNR1HDAC4HDAC6CNR2NPSR1 | |
| SCHEMBL9497720 | 0.95 | CNR1 (0.37) | CNR1HDAC4HDAC6CNR2PDK1 | |
| SCHEMBL22169758 | 0.80 | CCR2 (0.44) | CNR1HDAC4HDAC6CNR2NPSR1 | |
| SCHEMBL15474111 | 0.77 | ALDH1A1 (0.42) | CNR1HDAC4HDAC6CNR2NPSR1 | |
| Oxalic Acid SCHEMBL9795235 | 0.73 | CA1 (0.36) | DPP4TDO2 | |
| Oxalic Acid SCHEMBL9795230 | 0.73 | CA1 (0.36) | DPP4TDO2 | |
| Oxalic Acid SCHEMBL9795403 | 0.72 | EPHX2 (0.48) | PDK1PDK2PDK3PDK4 | |
| Oxalic Acid SCHEMBL9795398 | 0.72 | EPHX2 (0.48) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL9795342 | 0.72 | PDK1 (0.32) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL9994039 | 0.72 | CNR2 (0.41) | CNR1HDAC4HDAC6CNR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |